PT-141

PT-141 Overview

PT-141, also known as bremelanotide, is a cyclic peptide analogue derived from melanocortin-related peptide research. In laboratory settings, it is studied for its activity within the melanocortin receptor system and for how this receptor signaling influences broader neuroendocrine pathway biology.

Mechanism of Action & Applications

PT-141 is studied for agonist activity at melanocortin receptors, especially MC3R and MC4R. In research models, this makes it useful for examining melanocortin receptor pharmacology, central signaling pathways, peptide-receptor interactions, and broader neuroendocrine signaling dynamics.

Research History

PT-141 emerged from earlier melanocortin peptide research and is commonly described as a metabolite or derivative related to Melanotan II. Over time, it became a distinct research compound within the melanocortin field, with later development and characterization under the name bremelanotide.

Chemical Information

CAS Number: 189691-06-3
Molecular Formula: C₅₀H₆₈N₁₄O₁₀
Molecular Weight: 1025.2 g/mol
PubChem ID: 9941379
Purity: ≥99%