HGH 191aa

HGH 191aa Overview

HGH 191aa refers to the complete 191-amino-acid sequence of human growth hormone. In research settings, it is studied as the full-length form of the hormone responsible for activating growth hormone receptor signaling. Because it represents the intact sequence rather than a fragment or analogue, it is commonly used in models examining native growth hormone pathway behavior and receptor-mediated endocrine signaling.

Mechanism of Action & Applications

HGH 191aa is studied for its interaction with the growth hormone receptor, where receptor binding initiates signaling pathways associated with cellular growth, protein metabolism, and endocrine regulation. In laboratory research, this makes it useful for examining JAK-STAT pathway activity, IGF-1-related signaling, receptor binding dynamics, and broader growth hormone pathway biology. It is commonly used in studies involving endocrine signaling, receptor pharmacology, growth factor regulation, and full-sequence peptide hormone research.

Research History

Research on human growth hormone spans decades and played a major role in the development of modern peptide hormone biology. The 191-amino-acid form became an important research standard because it reflects the complete native sequence of pituitary-derived human growth hormone. Over time, it has been widely used in studies involving hormone structure, receptor activation, endocrine pathway signaling, and recombinant peptide production.

Chemical Information

CAS Number: 12629-01-5
Molecular Formula: C₉₉₀H₁₅₂₉N₂₆₃O₂₉₉S₇
Molecular Weight: 22124.12 g/mol
PubChem ID: 16132288
Purity: ≥99%