GLP-3 RT

GLP-3 RT Overview

GLP-3 RT is a multi-receptor peptide studied for activity across GLP-1, GIP, and glucagon pathways. In research settings, it is used to examine how these receptor systems work together and how combined receptor activity influences broader metabolic and endocrine signaling.

Mechanism of Action & Applications

GLP-3 RT is studied as a triple agonist at the GLP-1, GIP, and glucagon receptors. This receptor profile allows researchers to examine how simultaneous activation of incretin- and glucagon-related pathways affects intracellular signaling, hormone pathway coordination, and broader metabolic system responses. It is commonly used in research involving metabolic signaling, incretin receptor biology, multi-hormone pathway activity, and endocrine system regulation.

Research History

GLP-3 RT builds on earlier incretin research that first focused on GLP-1 receptor activity, then expanded to dual GLP-1/GIP agonists. Later development introduced glucagon receptor activity into the same peptide framework, leading to triple-agonist compounds like GLP-3 RT for more integrated pathway research.

Chemical Information

CAS Number: 2381089-83-2
Molecular Formula: C₂₂₁H₃₄₂N₄₆O₆₈
Molecular Weight: 4845.44 g/mol
PubChem ID: 474492335
Purity: ≥99%