Thymosin-Alpha-1

Thymosin-Alpha-1 Overview

Thymosin-Alpha-1, also known as thymalfasin, is a 28-amino-acid peptide originally identified from thymic tissue. In research settings, it is studied for its role in immune regulation and for how peptide-mediated signaling influences innate and adaptive immune pathway activity.

Mechanism of Action & Applications

Thymosin-Alpha-1 is studied for how it modulates immune signaling, particularly through Toll-like receptor-linked pathways and downstream effects on immune-cell communication. In laboratory research, this makes it useful for examining T-cell signaling, dendritic cell activity, innate immune pathway regulation, and broader peptide-driven immune response models.

Research History

Research on Thymosin-Alpha-1 began after thymic peptides were isolated and characterized in the 1970s. Later work established Thymosin-Alpha-1 as a distinct 28-amino-acid peptide and expanded its study into broader immune and peptide-signaling research.

Chemical Information

CAS Number: 62304-98-7
Molecular Formula: C₁₂₉H₂₁₅N₃₃O₅₅
Molecular Weight: 3108.31 g/mol
PubChem ID: 16130571
Purity: ≥99%