{"product_id":"igf-1-lr3","title":"IGF-1 LR3","description":"\u003ch4 data-start=\"384\" data-end=\"402\"\u003eIGF-1 LR3 Overview\u003c\/h4\u003e\n\u003cp data-start=\"404\" data-end=\"823\"\u003eIGF-1 LR3, also known as Long R3 IGF-1, is an 83-amino-acid analogue of insulin-like growth factor 1. It differs from native IGF-1 by an arginine substitution at position 3 and a 13-amino-acid N-terminal extension, changes that have been used in research to study altered receptor interaction, reduced binding to IGF-binding proteins, and extended activity in experimental systems.\u003c\/p\u003e\n\u003ch4 data-start=\"825\" data-end=\"859\"\u003eMechanism of Action \u0026amp; Applications\u003c\/h4\u003e\n\u003cp data-start=\"861\" data-end=\"1321\"\u003eIGF-1 LR3 is studied for its activity at the IGF-1 receptor, where receptor engagement is used to examine intracellular signaling related to growth, survival, and metabolic regulation. Because this analogue has reduced affinity for IGF-binding proteins compared with native IGF-1, it is commonly used in research involving receptor signaling duration, cell growth pathways, anabolic signaling models, and IGF-axis biology.\u003c\/p\u003e\n\u003ch4 data-start=\"1323\" data-end=\"1339\"\u003eResearch History\u003c\/h4\u003e\n\u003cp data-start=\"1341\" data-end=\"1747\"\u003eResearch on IGF-1 LR3 developed from broader work on insulin-like growth factor biology and the role of IGF-binding proteins in regulating peptide availability. Longer-chain analogues such as LR3 were designed to help researchers study how structural modifications change receptor activity, binding-protein interaction, and functional persistence in laboratory models.\u003c\/p\u003e\n\u003ch4 data-start=\"1749\" data-end=\"1769\"\u003eChemical Information\u003c\/h4\u003e\n\u003cp data-start=\"1771\" data-end=\"1921\"\u003eCAS Number: 946870-92-4\u003cbr data-start=\"1794\" data-end=\"1797\"\u003eMolecular Formula: C₄₀₀H₆₂₅N₁₁₁O₁₁₅S₉\u003cbr data-start=\"1834\" data-end=\"1837\"\u003eMolecular Weight: 9117.60 g\/mol\u003cbr data-start=\"1868\" data-end=\"1871\"\u003ePurity: ≥99%\u003c\/p\u003e","brand":"Phase 1 Peptides","offers":[{"title":"1 MG","offer_id":46106303889580,"sku":"P1P-IGF1","price":85.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0733\/6660\/1900\/files\/IGF-1_LR3_1MG.png?v=1775288756","url":"https:\/\/phase-1-peptides.myshopify.com\/products\/igf-1-lr3","provider":"Phase 1 Peptides","version":"1.0","type":"link"}